This case study reflects the health care waste management innovation of Health Environment and Climate Action Foundation (HECAF360) under the Water, Sanitation and Hygiene Sustainable Development Goal (WASH SDG) Innovation Fund in partnership with the local Plan International Nepal and the Health Care Without Harm network. This project has installed safe, sustainable health care waste management with smart autoclaving technology that incorporates remote monitoring devices. This system prevents open waste burning and keeps waste from going to the landfill, which reduces greenhouse gasses such as methane and carbon dioxide.